Question Date: 16/06/2023
Question: In case of congenital toxoplasmosis, the duration of treatment with sulfadiazine, pyrimethamine and leucovorin is
Options:
Correct Answer: 1 year
Explaination: Treatment/prevention of congenital toxoplasmosis<br>If in utero toxoplasmosis exposure is suspected<br>-Spiramycin can be administered in the first or early second trimester<br>- Pyrimethamine/sulfadiazine and leucovorin can be given in the late second or third trimester<br><br>Treatment with Pyrimethamine/sulfadiazine and leucovorin should be continued for 1 year after delivery and has been shown to improve neurologic outcomes
Reference: CONTINUUM (MINNEAP MINN) 2021;27(4, NEUROINFECTIOUS DISEASE):1105?1126