| 1 |
23/02/2024 |
A 36-year-old man presents with a 1-year history of gradual bilateral hearing loss, a sense of aural fullness, and progressively impaired balance. He has a history of juvenile cataracts, and his brother and father have similar difficulties with their hearing. A brain magneticresonance image (MRI) with contrast is shown. Which of the following is the most likely cause of his symptoms? |
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| 2 |
22/02/2024 |
A 32-year-old man presents to the emergency room with weakness, numbness, and paresthesias in his distal lower extremities that have ascended over the course of 2 days to the level of his hips. His hands are also now symptomatic. On examination, he is also noted to have no reflexes in his arms or legs. There was no preceding infection. Spinal fluid analysis reveals cytoalbuminologic disassociation, and a diagnosis of Guillain-Barr syndrome (GBS) is made. Laboratory evaluation performed on presentation was also notable for hyponatremia. Which is most likely to explain his hyponatremia? |
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| 3 |
21/02/2024 |
Which of the following condition do not impair procedural memory? |
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| 4 |
20/02/2024 |
A 50-year-old man experiences frequent recurrent pain on the left side of his throat, near his tonsils. He says that this feels like a hot poker. Assuming a radiographic evaluation is unrevealing, which of thefollowing is the appropriate first-line therapy? |
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| 5 |
19/02/2024 |
Which of the following layers of the retina does light first encounter after passing through the lens? |
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| 6 |
18/02/2024 |
A 25-year-old woman presents with a history of left arm automatisms and lip smacking, followed by a generalized convulsion. Her history is also remarkable for recurring headaches previously attributed as migraines. An axial magnetic resonance image (MRI) is shown. Which of the following is considered the most likely diagnosis? |
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| 7 |
17/02/2024 |
All of the following medications can precipitate a myasthenic crisis except? |
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| 8 |
16/02/2024 |
Which of the following is the most serious potential adverse effect of mitoxantrone? |
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| 9 |
15/02/2024 |
The figure below shows a 120-second segment from an overnight polysomnogram. Which of the following is demonstrated in the picture? |
|
| 10 |
14/02/2024 |
In median nerve somatosensory evoked potentials, theN13 peak corresponds with which anatomicallocation? |
|
| 11 |
13/02/2024 |
Idiopathic intracranial hypertension may commonly cause which of the following secondary symptoms? |
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| 12 |
12/02/2024 |
An 83-year-old man with cognitive decline presents with altered mental status. The patients vital signs are normal and there has been no recent illness or fever. His laboratory tests (including coagulation profiles) are largely unremarkable and show no electrolyte abnormalities or infection. Which of the following is the most likely cause of the finding shown? |
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| 13 |
11/02/2024 |
In neuropsychological testing, a pathological lack of motivation not from a mood disorder results from a lesion to which circuit? |
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| 14 |
10/02/2024 |
A 35-year-old female presents to the emergency department with leg weakness. She has had several days of nausea, abdominal pain, and constipation before her arrival at the emergency room (ER). She was dragging her feet while walking and even had a fall. Her husband mentioned she had visual hallucinations and confusion during this same time. While in the ER, she is tachycardic with labile blood pressures. She is somnolent but arousable and disoriented. Her neurological examination reveals intact cranial nerves, normal strength in the arms, decreased strength throughout the legs, and absent patellar reflexes with preserved ankle jerk reflexes. She has normal sensation in all her extremities. Which of the following tests would be most helpful in making the diagnosis? |
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| 15 |
09/02/2024 |
A 50-year-old man with acquired immunodeficiency syndrome (AIDS) presents to the hospital with severaldays of confusion, followed by a decline in level of consciousness. A computed tomography scan of thebrain demonstrates diffuse atrophy, but no acute findings. A lumbar puncture is performed, and openingpressure is 60 cm (normal is <20 cm). The spinal fluid further demonstrates a glucose of 10 mg/dL (normal is4580 mg/dL), protein of 140 mg/dL (normal is 1545 mg/dL), normal red blood cells, and 9 whiteblood cells/mL (normal is <5 cells/mL) with a lymphocytic predominance. Based on your suspecteddiagnosis and while awaiting further studies, which of the following is the best course of action afterremoving a large volume of cerebrospinal fluid (CSF)? |
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| 16 |
08/02/2024 |
An 82-year-old male with a history of Parkinson disease presents to the emergency department with headaches and mild left-sided weakness. An emergent computed tomography scan of his brain demonstrates a small, right-sided intracerebral hemorrhage in the internal capsule. His blood pressure remains above 220 systolic despite two doses of intravenous labetalol. His wife mentions he was recently started on a new medication for his Parkinson disease. Which of the following is the most likely causative agent? |
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| 17 |
07/02/2024 |
A 2-month-old was evaluated by his pediatrician for intermittent episodes of forced head turns to the left. Each time, the event lasts for approximately 6 hours but is not associated with any distress to the infant. There are no abnormal movements of the eyes or limbs. What should the advice be to the parents at this time? |
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| 18 |
06/02/2024 |
An 8-month-old is noted to have global developmental delay, nystagmus, and appears to have episodes of panting. A magnetic resonance image (MRI) is shown. Which of the following signs is not associated with this condition? |
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| 19 |
05/02/2024 |
Which of the following is the chief component of cerebrospinal fluid (CSF) reabsorption? |
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| 20 |
04/02/2024 |
A 40-year-old woman underwent muscle biopsy for progressive weakness, among other symptoms. Which of the following is her most likely diagnosis based on the image shown? |
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| 21 |
03/02/2024 |
Which of the following is not a subtype of vascular cognitive impairment as per the VICCCS diagnostic criteria? |
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| 22 |
02/02/2024 |
2 A 33-year-old previously healthy woman has an acute onset of neck pain, headache, and decreased vision on the right field. She also complains of heaviness in her right arm and difficulty speaking. Her examination shows nonfluent aphasia, a right homonymous hemianopsia, and right hemiparesis. Magnetic resonance imaging confirms the suspected etiology of her symptoms, from which a key T1 fat-saturated image is shown. Otherwise, workup is negative. What isthe most likely etiology of her condition? |
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| 23 |
01/02/2024 |
Which of the following is not true regarding immune mediated neurological conditions associated with immune checkpoint inhibitors? |
|
| 24 |
31/01/2024 |
All of the following factors are commonly associated with central pontine /extrapontine myelinosis except: |
|
| 25 |
30/01/2024 |
Which of the following differentiates ATLD(Ataxia telangiectasia like disorders) from Ataxia telangiectasia? |
|
| 26 |
24/01/2024 |
All of the following are broad spectrum antiseizure medications except |
|
| 27 |
23/01/2024 |
Exercise induced rhabdomyolysis can occur in all except |
|
| 28 |
22/01/2024 |
Factors showing positive association with seizure free outcome after resective surgery are all except |
|
| 29 |
21/01/2024 |
Which of the following is not a risk factor for development of post encephalitic epilepsy? |
|
| 30 |
20/01/2024 |
Which of the following is not true regarding CADASIL? |
|
| 31 |
19/01/2024 |
Which of the following neurological conditions pose increased risk to neuraxial anesthesia in pregnancy? |
|
| 32 |
18/01/2024 |
Which of the following MRI Imaging feature suggests aggressive behavior/ higher grade of meningioma? |
|
| 33 |
17/01/2024 |
Which of the following statement regarding "Treatment induced Neuropathy of Diabetes" is false? |
|
| 34 |
16/01/2024 |
Which of the following neurologic syndrome does not show association with Rheumatoid Arthritis? |
|
| 35 |
15/01/2024 |
Which of the following is true about acquired hepato-cerebral degeneration? |
|
| 36 |
14/01/2024 |
Which of the following drug show strong recommendation for use in excessive day time sleepiness in Narcolepsy? |
|
| 37 |
13/01/2024 |
Medical and genetic conditions not associated with high risk of Obstructive sleep apnea are: |
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| 38 |
12/01/2024 |
All of the following are red flags indicating a genetic etiology or a CP mimic in a child with diagnosis of Cerebral Palsy except: |
|
| 39 |
11/01/2024 |
Which of the following neurological manifestation is less likely to occur with POEMS syndrome? |
|
| 40 |
10/01/2024 |
Which of the following is the drug of choice in patient with RBD and clinical depression? |
|
| 41 |
09/01/2024 |
Which of the following is not found in IBM? |
|
| 42 |
08/01/2024 |
Which of the following is false about DMD? |
|
| 43 |
07/01/2024 |
Which of the following myositis specific antibody does not have cancer association? |
|
| 44 |
06/01/2024 |
Which of the following drugs are not recommended as neuropathic pain medication for chemotherapy induced peripheral neuropathy(CIPN)? |
|
| 45 |
05/01/2024 |
All of the following are red flags suggesting a diagnosis other than GBS except |
|
| 46 |
22/12/2023 |
Dopamine beta hydroxylase converts dopamine to which of the following? |
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| 47 |
21/12/2023 |
A 58yrs man CKD with urinary tract infection on Cefepime, was referred after a GTCS f/b persistent altered state. EEG is shown below. EEG and sensorium improved after iv lorazepam. What is the likely diagnosis? |
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| 48 |
20/12/2023 |
What is the localization of this inter-ictal EEG? |
|
| 49 |
19/12/2023 |
What is the ictal onset in the EEG shown below? |
|
| 50 |
18/12/2023 |
Name the anomaly seen in the MRI here: |
|
| 51 |
17/12/2023 |
The standard 10-20 schema of EEG recording was developed by... |
|
| 52 |
16/12/2023 |
In myelopathy associated with copper deficiency, all of the following are seen except: |
|
| 53 |
15/12/2023 |
Which of the following is innervated by anterior interosseous nerve? |
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| 54 |
14/12/2023 |
4 What is the classical EEG finding?<br><br>6 months baby girl<br>Multiple episodes of head drops<br>Occurring in clusters especially after awakening from sleep<br>No perinatal complications, social and developmental milestones preserved<br>Inter-ictal EEG is shown besides. |
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| 55 |
13/12/2023 |
What is the typical MRI anomaly? |
|
| 56 |
12/12/2023 |
Which of the following is the most common cause of early-onset autosomal-dominant Alzheimer disease? |
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| 57 |
11/12/2023 |
A 58-year-old man presents with a 2-months history of gradually progressive right hemiparesis. A contrast-enhanced magnetic resonance image of the brain is shown here. What is the most likely diagnosis for the lesion shown? |
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| 58 |
10/12/2023 |
A 63-year-old man presents to the clinic for burning pain in both feet, causing discomfort while walking. He also feels as if something is stuck in his shoe at times. He complains of tenderness to palpation of his feet. His deep tendon reflexes are normal. Which of the following is not true regarding the most likely diagnosis? |
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| 59 |
09/12/2023 |
Olfactory sensation travels from the olfactory bulb toall of the following structures, except? |
|
| 60 |
08/12/2023 |
Which of the following suggests that a patients vertigo is from a brainstem or cerebellar lesion, as opposed to a peripheral cause? |
|
| 61 |
07/12/2023 |
Which of the following medications slows the metabolism of dopamine in the central nervous system? |
|
| 62 |
06/12/2023 |
What is the most likely etiology for the EEG shown below? |
|
| 63 |
05/12/2023 |
The Wisconsin Card Sorting Test is helpful in determining functional abnormalities in which domain of cognitive function? |
|
| 64 |
04/12/2023 |
According to the Carotid Revascularization Endarterectomy vs. Stenting Trial (CREST), which is associated with a periprocedural increased risk of stroke? |
|
| 65 |
03/12/2023 |
What is the EEG phenomenon shown below? |
|
| 66 |
02/12/2023 |
After 3 days of a febrile illness, a previously well 19 years old developed focal seizures with loss of awareness. The seizures progressed to generalised tonic-clonic seizures and convulsive status epilepticus requiring sedation and ventilation in intensive care. cEEG during in ICU shown below. What would be the likely diagnosis? |
|
| 67 |
01/12/2023 |
What does the inter-ictal EEG finding s/o? |
|
| 68 |
30/11/2023 |
A 10 years old boy presents with GTCS, h/o multifoal Myoclonus since last 2 yrs duration. For past 6m gradual decline in scholastic performance. Brother has similar epilepsy and was vaccinated per schedule. What is likely diagnosis? |
|
| 69 |
29/11/2023 |
This EEG phenomenon can be seen in: |
|
| 70 |
28/11/2023 |
A 10 years boy woke up with Twitching of right face and right hand, was dysarthric for few seconds, underwent EEG shown below.. What would be the next step? |
|
| 71 |
27/11/2023 |
A 42-year-old male presents with memory loss over the last several months. He notes antecedent arthralgia, low-grade fevers, skin hyperpigmentation, and frequent diarrhea. On examination he has mild rigidity in his upper extremities, and concurrent slow pendular movements of the eyes and contraction of the masseter. Which of the following is the most likely diagnosis? |
|
| 72 |
26/11/2023 |
A 36yrs lady with refractory epilepsy, failed multiple ASMs, shows following imaging findings.What are the further treatment options? |
|
| 73 |
25/11/2023 |
A 6-year-old girl presents with involuntary jerking movements of her left leg followed by left arm since past 2 years. She had several episodes of this that would last for hours before stopping spontaneously and had no major response to levetiracetam. In the last 2 weeks, the patients mother has noted that she seems unaware during parts of these episodes and may have had twitching of the left side of her face. Electroencephalogram reveals right hemispheric spikes. A magnetic resonance image (MRI) of her brain is shown. Which of the following is the best treatment for this condition? |
|
| 74 |
24/11/2023 |
All of the below statements are true for Lennox-Gastaut Syndrome except..? |
|
| 75 |
23/11/2023 |
What does the EEG depict? |
|
| 76 |
22/11/2023 |
In an ICU EEG if there are multiple machines how do you advise earthing |
|
| 77 |
21/11/2023 |
A 16-year-old male suffers sharp, stabbing pain across his entire head each time he coughs. The pain is severe but resolves quickly after coughing. Which of the following should be done? |
|
| 78 |
20/11/2023 |
EEG potentials are manly generated by |
|
| 79 |
19/11/2023 |
4yrs girl, had one episode of fall with transient unresponsiveness at school prayer, EEG showed below is s/o? |
|
| 80 |
18/11/2023 |
What is the EEG record s/o? |
|
| 81 |
17/11/2023 |
A 42-year-old man develops vertical diplopia, which seems worst when watching television from bed. On examination, he has left hypertropia, which is exacerbated with downward gaze of an adducted left eye. If he tilts his head to the right, the vision improves. Which of the following is the affected cranial nerve? |
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| 82 |
16/11/2023 |
An 8-year-old boy presents with frequent staring episodes while in class. Based on the electroencephalogram (EEG) shown, which of the following is the most appropriate medication for this patient? |
|
| 83 |
15/11/2023 |
In an electroencephalogram (EEG), increasing the high-pass filter will result in which of the following? |
|
| 84 |
14/11/2023 |
A 23-year-old female presents to the clinic for evaluation of a headache. She is currently 14 weeks pregnant. She complains of a holocephalic headache for the last week, which is worsening in intensity. The headache is worse at night and causes blurry vision.Her neurological examination is remarkable for bilateral papilledema. The sagittal T1 magnetic resonance image (MRI) is shown here. Which of the following is the most likely diagnosis? |
|
| 85 |
12/11/2023 |
50yrs lady presented with gradual onset ataxia and left ear hearing loss. MRI is shown below. The likely diagnosis is: |
|
| 86 |
10/11/2023 |
The MRI of lumbar spine shown below shows which abnormality? |
|
| 87 |
09/11/2023 |
he unique combination of 6th and 12th cranial nerve palsies localising to lesions at clivus is termed as |
|
| 88 |
08/11/2023 |
Inverted patellar reflex localizes the site of lesion to |
|
| 89 |
07/11/2023 |
The blood supply to inferior and mesial portion of temporal lobe is by which of the following |
|
| 90 |
05/11/2023 |
The commonest pathological substrate in surgical series of refractory epilepsy in children is.. |
|
| 91 |
04/11/2023 |
Which of the following tumors is most commonly associated with opsoclonus-myoclonus? |
|
| 92 |
03/11/2023 |
A 56-year-old man with a history of treated liver abscess 1 month ago presents with vertigo, gait ataxia and tremors. MRI is as shown below. What is the diagnosis? |
|
| 93 |
02/11/2023 |
Which of the following is the most common level for spinal cord infarction? |
|
| 94 |
01/11/2023 |
A 24-year-old man with DYT1 dystonia has become effectively disabled over the past 4 years. His dystonia was initially controlled with targeted botulinum toxin injections and various oral medications, but over the past 4 years, these treatments have become less effective and his dystonia has continued to generalize. He is no longer ambulatory and has recently developed decubitus ulcers in his buttock region. He is considering surgery<br><br>Which of the following surgical targets is most appropriate for deep brain stimulation? |
|
| 95 |
31/10/2023 |
At the level of C3, the anterior and posterior spinal arteries originate primarily from which of the following blood vessels? |
|
| 96 |
30/10/2023 |
A 15-year-old girl is referred for a neurologic evaluation by her primary care physician because of choreic movements of several years duration. The movements interfere with her ability to participate in sports, crafts, and writing, but her mother does not think that they are progressively worsening. The patients father does not live with her but reportedly had similar movements for several years. Her medical history is remarkable for short stature, hypothyroidism, and moderately significant developmental delay<br><br>Which of the following is the most likely cause of her chorea? |
|
| 97 |
29/10/2023 |
Which of the following is the most appropriate management for patients with neurogenic bladder due to spinal cord injury? |
|
| 98 |
28/10/2023 |
A 47-year-old woman is referred for evaluation of imbalance. She reports that when she stands still she feels very unsteady and dizzy but when she walks she no longer has associated unsteadiness. The symptoms have been progressively worsening over time, and her primary care doctor was unable to explain her symptoms. On examination, she has normal blood pressure and pulse with no difference in the supine or standing position. A very low-amplitude postural tremor is evident in her arms, with no rigidity or bradykinesia. When she stands, she displays a subtle, high-frequency tremor in her legs and reports feeling off-balance. |
|
| 99 |
27/10/2023 |
Which drug is least likely to cause idiopathic intracranial hypertension? |
|
| 100 |
26/10/2023 |
Neurons with cell bodies in the intermediolateral cell column at the T4 level of the spinal cord send their axons to which of the following structures or pathways? |
|
| 101 |
25/10/2023 |
A 29-year-old woman with multiple sclerosis presents because of a new-onset tremor in her right arm that she first noted upon awakening that morning. The tremor is quite disabling, and she is distressed by the symptom as it interferes with her ability to hold utensils to eat. On examination, a large-amplitude tremor is evident in the patients right arm, which is present at rest and worse when her right arm is held out in front of her body. It also clearly worsens as she approaches a target<br><br>Which of the following is the most likely localization of the lesion that is causing the tremor? |
|
| 102 |
24/10/2023 |
Which of these histological features is the most sensitive finding in dermatomyositis? |
|
| 103 |
23/10/2023 |
Which of these neuroimaging statement s is true in spontaneous intracranial hypotension? |
|
| 104 |
22/10/2023 |
A 24-year-old man began to experience Lhermitte phenomenon 2 months after receiving radiation therapy for Hodgkin disease. When seen in neurologic consultation 1 week after the onset of his symptoms, he has a normal general examination and neurologic examination. Imaging studies show no evidence of recurrent lymphoma. MRI scans of the brain, cervical spine, and thoracic spine are all normal. Which of the following is the most likely prognosis? |
|
| 105 |
21/10/2023 |
A 60-year-old man has had problems with REM sleep behavior disorder and central sleep apnea for at least 5 years. Over the past 2 years, he has developed progressive cerebellar deficits, orthostatic hypotension, symptoms suggestive of neurogenic bladder, and dry mouth<br><br>What is the most likely cause of his syndrome? |
|
| 106 |
20/10/2023 |
Which of these statements is true regarding immune mediated necrotizing myopathy? |
|
| 107 |
19/10/2023 |
Which of these non headache symptoms have not been reported in spontaneous intracranial hypotension? |
|
| 108 |
18/10/2023 |
A 65-year-old man presents to the emergency department with neck pain after a fall. Short tau inversion recovery (STIR) MRI of the cervical spine shows abnormal hyperintensity within the C5 vertebra. A follow-up CT scan of the cervical spine is obtained for a dedicated examination of that level of the spine, which demonstrates a fracture of the C5 vertebra. Which of the following radiologic findings is most suggestive of a benign etiology of this fracture? |
|
| 109 |
17/10/2023 |
An 8-year-old girl presents with jerky movements of the hands and arms (noted since 3 years of age). She was initially diagnosed with essential tremor based on a family history of perceived tremor in her mother. Now that the patient is in second grade, the jerks have impaired her ability to write. On examination, she is noted to have resting and action-induced axial-predominant myoclonic jerks. While holding a pencil to write, she displays an abnormal hand posture and exacerbation of the myoclonus in the neck<br><br>Which of the following is the most likely diagnosis? |
|
| 110 |
16/10/2023 |
In dermatomyositis, which of these muscle specific antibodies is associated with risk of cancer? |
|
| 111 |
15/10/2023 |
Which statement is not true regarding headache in spontaneous intracranial hypotension? |
|
| 112 |
14/10/2023 |
A 45-year-old woman with a history of migraine headaches with aura and cognitive difficulties developed a transient episode of right hemiparesis that resolved in 15 minutes <br><br>Neurologic examination reveals difficulties with attention and a spastic gait<br>She has family history of migraine and dementia in her mother and ischemic stroke in her brother <br>An MRI examination reveals symmetric increase in T2 signal in the subcortical white matter, including the temporal pole and the external capsule<br>These findings are suggestive of a mutation affecting which of the following genes? |
|
| 113 |
13/10/2023 |
A 9 year old boy was brought to a neurologist by his parents, who noticed that the child preferred to stay alone in his own world, would not make eye contact with people, would do stereotypic limb movements, he was resistant to change and wouldnt mingle with his friends. His developmental history was normal and examination did not reveal any dysmorphic features. His neurological examination was normal. Neurologist diagnosed him as autism spectrum disorder<br><br>Which is the next test he is most likely to order? |
|
| 114 |
12/10/2023 |
A 51-year-old woman who presented with a 1-year history of progressive left cervical radicular pain and dysesthesia in her left middle finger was found to have a minimally enhancing intradural extramedullary mass adjacent to the left C7 nerve root. The mass was resected, and histologic examination revealed a schwannoma with no malignant features. Which of the following subsequent management approaches is most appropriate? |
|
| 115 |
11/10/2023 |
A 66-year-old man is referred for evaluation of right arm clumsiness. The symptoms developed 2 years ago with difficulty writing and manipulating tools. Over the next 2 years, the symptoms gradually worsened, and he felt as if the arm became much less useful. At times, he felt that the right arm was not under my control. When he was distracted, the arm would rise on its own and do things that he had not intended. He also noted overall slowness with tasks. On examination, he has full strength in the right arm with associated rigidity and bradykinesia and is unable to demonstrate how to salute, brush his teeth, or screw in a lightbulb. He also extinguishes the sensory response on the right arm to dual simultaneous sensory stimulation. When walking, his right arm becomes dystonic <br><br>What is the most likely diagnosis? |
|
| 116 |
10/10/2023 |
Which of these statements is not true regarding Facioscapulohumeral dystrophy? |
|
| 117 |
09/10/2023 |
Which statement is not true regarding menstrual migraine? |
|
| 118 |
08/10/2023 |
Which of the following enzyme is responsible for clopidogrel resistance due to poor metabolism? |
|
| 119 |
07/10/2023 |
Which of the following neuropsychological test measures is used to assess set shifting? |
|
| 120 |
06/10/2023 |
A 23-year-old man is involved in a motorcycle accident and sustains a traumatic spinal cord injury with complete paraplegia and a T4 sensory level. Which of the following durations of anticoagulation is most appropriate to prevent deep venous thrombosis in this patient? |
|
| 121 |
05/10/2023 |
Which of the following is the most common appearance of pure psychogenic gait disorder? |
|
| 122 |
04/10/2023 |
Which of these patterns of weakness is not seen in dysferlinopathy? |
|
| 123 |
03/10/2023 |
Which statement is false regarding Glossopharyngeal neuralgia? |
|
| 124 |
02/10/2023 |
32 year old lady presented with optic neuritis and paraparesis. MRI brain and orbit and spine showed demyelinating plaques. There was long segment myelitis and optic neuritis involving the optic chiasma. CSF Routine showed 5 cells and 80mgdl proteins. Serum NMO antibody was positive. She was started on Inj Methylprednisolone and azathioprine 50 mg 1-0-1. Her symptoms improved however three weeks later she developed fever and pancytopenia<br><br>Which of the following laboratory test results could explain her pancytopenia cause? |
|
| 125 |
01/10/2023 |
46 year old male developed insidious onset progressive chorea, dystonia, and psychosis. His wife filed for divorce. He would abuse his wife, and had hypersexuality. He was a very sober man previously. He gradually started having cognitive dysfunction-executive dysfunction, inattention, lost his job and had to be shifted to a rehab center. There was similar history in father who died at the age of 50 years <br><br>His MRI brain showed mild cerebral atrophy<br>CAG repeats in HTT gene were normal<br> Which is the genetic test most likely to be abnormal in his case? |
|
| 126 |
30/09/2023 |
Which of the following patterns of neurologic deficit would be most likely after a hyperextension neck injury in a 72-year-old woman with a history of cervical spondylosis? |
|
| 127 |
29/09/2023 |
A 57-year-old woman is referred for evaluation of abnormal movements. She was diagnosed with Parkinson disease 5 years ago by her family physician and has been maintained on levodopa for the past 4 years with escalating dose adjustments. Although her Parkinson disease is under good control, she has recently developed occasional unwanted movements of her arms and legs that have been bothersome to her. She is an accountant and feels that the movements interfere with her relationship with her clients <br><br>Which of the following medications should be considered to reduce these movements? |
|
| 128 |
28/09/2023 |
Which of these features is not a hallmark of a neurogenic process in muscle biopsy? |
|
| 129 |
27/09/2023 |
A 76 year old lady presented with numbness on right side of chin. There was no history of recent dental procedure. Examination showed numbness over the chin on the right side, rest of the cranial nerves being normal <br><br>Which statement is true regarding this condition? |
|
| 130 |
26/09/2023 |
Which of the following is false about imprinting? |
|
| 131 |
25/09/2023 |
70 year old gentleman presented with 3 years of insidious onset progressive cognitive decline, tremors, bradykinesia and psychosis. He would see multiple tiny humans dancing around him, jumping and breaking objects. He would get amused by these tiny creatures. No one around him would see them. He had few good days and few days when he would just keep staring at the wall for hours. His son also reported enactment of dreams in sleep <br><br>His MRI brain showed mild cerebral atrophy <br>Which of the following statements is correct regarding his investigations and treatment? |
|
| 132 |
24/09/2023 |
A 67-year-old man presents with 2 days of severe lumbar back painassociated with bilateral sciatica, leg weakness, urinary retention, fecalincontinence, and sexual dysfunction. Spine MRI studies show amassive midline disk herniation at L4-L5 with compression of the caudaequina. The patient is taken for urgent surgical decompression. Whichof the following symptoms is most likely to improve from this surgery? |
|
| 133 |
23/09/2023 |
A 53-year-old man presents for evaluation and treatment of a tremor. He reports 6 years of progressively worsening tremor in his hands that interferes with his handwriting and performance of fine motor tasks. He works in construction, and the tremor has impaired his ability to use a screwdriver accurately. The tremor improves transiently with alcohol. He has a strong family history of tremor and a medical history of asthma and diabetes. On examination, he has a bilateral 6-Hz to 8-Hz postural tremor in his upper extremities. No rigidity, bradykinesia, or gait instability is evident<br><br>Which of the following medications is most appropriate for this patient? |
|
| 134 |
22/09/2023 |
Which of these statements is true regarding MuSK myasthenia gravis? |
|
| 135 |
21/09/2023 |
Which statement is not true regarding trigeminal neuralgia? |
|
| 136 |
20/09/2023 |
A 6 year old girl was brought to her pediatrician in view of refractory epilepsy, neuroregression and abnormal involuntary movements. She had intellectual disability, abnormal eye and head movements and chorea.<br><br> Her examination revealed a spastic ataxic gait with dystonia.<br><br> She had recurrent daily episodes of generalized tonic clonic seizures which was pharmacoresistent. Her CSF studies showed low glucose level and normal proteins and cells.<br><br> What treatment will you prescribe for her? |
|
| 137 |
19/09/2023 |
58 year old male presented with subacute onset rapidly progressive behavioral disturbances, headache, right upper limb weakness and right upper limb focal motor seizures with preserved awareness.<br><br> MRI Brain showed patchy confluent asymmetric T2 weighted hyperintense signals and GRE showed multiple tiny area of blooming in the same areas.<br><br>CSF routine showed 10 Wbc and 76 mgdl proteins, sugar was normal.<br><br> CSF bio fire was negative and neoplastic cells were negative.<br><br>What is the most likely diagnosis? |
|
| 138 |
18/09/2023 |
A patient with a chronic spinal cord injury develops extreme elevations of blood pressure, bradycardia, diaphoresis, and flushing whenever he develops severe constipation. What is the lowest level of spinal cord injury associated with this complication of spinal cord injury? |
|
| 139 |
17/09/2023 |
A 43-year-old woman presents with 5 years of a gradually progressive ataxic gait disorder and dysarthria. MRI of her brain shows atrophy of the cerebellum. She has also been diagnosed with retinal macular degeneration |
|
| 140 |
16/09/2023 |
Which of these eye signs is not consistent with ocular myasthenia gravis? |
|
| 141 |
15/09/2023 |
A 55 year old hypertensive male presented with sudden excruciating headache which peaked in a minute. It was associated with vomiting. Which of these is unlikely to be the cause of his headache |
|
| 142 |
14/09/2023 |
Which of the following statements is false regarding the disease of this child? |
|
| 143 |
13/09/2023 |
Which of the following is a biomarker of Chronic Traumatic encephalopathy? |
|
| 144 |
12/09/2023 |
A 19-year-old woman living in a region of Africa in the midst of a severe drought develops leg weakness that progresses over the course of a day to complete inability to move her legs. Examination is notable for cachexia and spastic paraplegia with normal sensory function. Which of the following is the most likely cause of her paraplegia? |
|
| 145 |
11/09/2023 |
A 61-year-old right-handed man presents with a 6-month history of tremor in the left hand. He reports that it has been more difficult for him to button his shirt and tie his shoes. On examination, he has a resting tremor of the left arm, bradykinesia of the left arm and hand, rigidity in the left arm, and limited left arm swing when walking<br><br> Which of the following clinical symptoms would most likely be present on review of systems in this patient? |
|
| 146 |
10/09/2023 |
Myokymia is not seen in which of these disorders? |
|
| 147 |
09/09/2023 |
Migraine like headache is not a feature of which neurological condition? |
|
| 148 |
08/09/2023 |
Batwings dilatation of sylvian fissures is seen in? |
|
| 149 |
07/09/2023 |
A 40 year old gentleman, former football player for 20 years, committed suicide by shooting himself. He had developed insidious onset gradually progressive executive dysfunction, memory disturbances and behavioral changes over 10 years. He was highly compulsive and lost his money in gambling. He became extremely short tempered and irritable was depressed all the time. His MRI Brain showed mild cortical thinning. CSF A beta 42 levels were normal and CSF tau was elevated. One day he expressed desire to learn shooting and then killed himself. What is the most likely cause of his dementia? |
|
| 150 |
06/09/2023 |
A 53-year-old man presents with flaccid paraparesis and sphincter dysfunction which developed gradually over 4 months. MRI imaging of the spinal cord and cauda equina is unremarkable. His past history is significant for hyperlipidemia, hypertension, and a history of testicular cancer treated with orchiectomy and radiation 14 years ago. Complete blood count and differential are normal. What is the most likely cause of his symptoms? |
|
| 151 |
05/09/2023 |
Six days after resuscitation from a cardiorespiratory arrest, a 61-year-old man is experiencing frequent action-induced myoclonic jerks that impair his ability to fully participate in physical therapy. Which of the following medications should be prescribed as a first-line agent to reduce the myoclonus? |
|
| 152 |
04/09/2023 |
Which of these statements is not true regarding neuromyotonia (Isaacs syndrome)? |
|
| 153 |
03/09/2023 |
Which drug may be used safely for acute attack of migraine in pregnancy? |
|
| 154 |
02/09/2023 |
A 6 year old girl was brought to the emergency department with fever, vomiting, altered sensorium. Her MRI Brain and lumbar puncture was normal.<br><br> Electrolytes, renal and liver function tests were normal. She had metabolic acidosis and a characteristic burnt sugar odor. Her serum amino acids showed elevated levels of leucine, isoleucine, valine, and their keto acid derivatives.<br>After supportive aggressive acute therapy what will be your diet prescription for her |
|
| 155 |
01/09/2023 |
37 year old male developed 3 year insidious onset gradually progressive cognitive decline, memory disturbances, executive dysfunction and mild myoclonic jerks. Positive family history of early onset dementia in mother and maternal aunt. His genetic testing was done which showed PSEN1 mutation. His younger brother, who was asymptomatic, became anxious and wanted to know his genetic profile. His detailed neuropsychological testing is normal. What will you do? |
|
| 156 |
31/08/2023 |
A 25-year-old woman squats and attempts to help her roommate lift a heavy chest to move it from one room to another. She strains significantly, but is unable to lift and move her end. Within minutes she develops weakness of both legs, which worsens during the hour it takes her to present to the emergency department. She has also developed loss of temperature and pain sensation in her legs below T9 and is unable to void her bladder. A spine MRI shows no evidence of disk herniation or vertebral fracture<br><br>What is the most likely cause of her spinal cord injury? |
|
| 157 |
30/08/2023 |
Patients who develop symptomatic Huntington disease before the age of 20 years typically have which of the following manifestations? |
|
| 158 |
29/08/2023 |
A 75 year old diabetic is diagnosed with multiple myeloma. He has renal failure with serum creatinine of 3.1 mgdl. He is started on chemotherapy consisting of dexamethasone, lenalidomide and bortezomib. After the third cycle, the patient develops a severe painful neuropathy. Which of these would be the most likely diagnosis? |
|
| 159 |
28/08/2023 |
Which statement is true regarding migraine with aura? |
|
| 160 |
27/08/2023 |
A male newborn appears well for the first 24 hours after a term vaginal delivery but then refuses feeding and becomes irritable with rapidly progressive lethargy<br>On presentation, he is afebrile but unresponsive and experiences convulsions after which he is intubated<br>Lab studies reveal a normal WBC, a significantly elevated ammonia level, decreased plasma level of citrulline, and an elevated urine orotic acid.<br>The presentation is most consistent with a deficiency in which of the following? |
|
| 161 |
26/08/2023 |
67 year old male, presented with 2 month history of subacute onset progressive sleep disturbances, sleep apnea, stridor, myoclonus, cognitive impairment<br><br>MRI revealed following abnormality. Which of the following tests will you order? |
|
| 162 |
25/08/2023 |
46-year-old woman presents with sensory loss and paresthesia in her upper extremities and across her upper chest, with weakness in her intrinsic handmuscles bilaterally. The symptoms began about 2 years ago, initially involving a much narrower region, but the symptoms have gradually spread. She wasinvolved in a severe car accident 3 years ago and has had neck pain ever since,but she sustained no fractures or head injury. Her examination is notable forweakness and atrophy of the intrinsic hand muscles, brisk lower extremityreflexes, and loss of pain and temperature sensation in the C5 through T2dermatomes bilaterally, with normal sensation above and below those levels.MRI scan shows syringomyelia centered at C8 but extending up to C4 and downto T2. Which of the following patterns of upper extremity nerve conduction study results would be most typical in this scenario? |
|
| 163 |
24/08/2023 |
A 68-year-old man with a long-standing history of schizoaffective disorder is referred to the clinic for abnormal movements. He reports that his neck becomes stuck and twisted and that it has been harder for him to write over the past 3 months. Medications include sertraline, venlafaxine, lithium, risperidone, and zolpidem. Examination demonstrates dystonic posturing of the neck with associated head tremor and writing-induced dystonia of the right hand<br><br>Which medication is likely responsible for his neurologic presentation? |
|
| 164 |
23/08/2023 |
A 65 year old male presents with painful neuropathy since a year. He has significant weight loss. On examination, he has distal weakness with sensory loss in arms and legs. There is postural hypotension and leg edema with cachexia. He is non diabetic and work up for malignancy and HIV is negative. Which of these statements is true regarding diagnosis of primary amyloid neuropathy? |
|
| 165 |
22/08/2023 |
Which of these conditions is not a cause of nocturnal headache in the elderly? |
|
| 166 |
21/08/2023 |
Match the genetic mechanism of Duchene muscular dystrophy with the correct drug |
|
| 167 |
20/08/2023 |
Which is the hallmark of logopenic variant Primary progressive aphasia? |
|
| 168 |
19/08/2023 |
CSF can be obtained from lumbar sac and from ventricles for analysis. What is the difference between CSF obtained from lumbar sca and ventricle? |
|
| 169 |
18/08/2023 |
Which of the following physiologic consequences is most likely to occur within hours of a complete spinal cord injury at the T2 level? |
|
| 170 |
17/08/2023 |
A 43-year-old woman presents with the sudden onset of severe dystonic posturing of her right hand and forearm. It is painful and constant<br><br>Which of the following concomitant neurologic signs on examination might suggest a psychogenic or functional movement disorder? |
|
| 171 |
16/08/2023 |
Which of these proteins is not associated with familial amyloid polyneuropathy? |
|
| 172 |
15/08/2023 |
A 40 year old migraineur reports brief shock like pain over the parietal scalp lasting seconds. They occur at variable frequency through the day and occur on either side. There are no precipitating factors and no autonomic features. Neurological examination is normal. What is the most likely diagnosis? |
|
| 173 |
14/08/2023 |
Which of the following genetic tests should best detect a balanced chromosomal translocation? |
|
| 174 |
13/08/2023 |
A 56 Year old lady, developed subacute onset rapidly progressive gait ataxia, anterograde and retrograde amnesia, executive dysfunction, confabulation, apathy, as well as affective and social-cognitive impairments. Her oculomotor examination revealed ophthalmoparesis. She had multiple episodes of vomiting, anorexia prior to developing the neurological symptoms. MRI revealed bilateral Dorsomedial thalamic hyperintense signals. What is the most likely diagnosis? |
|
| 175 |
12/08/2023 |
Serum glucose level is often obtained while performing lumbar puncture for CSF examination for correlation with CSF glucose level. What is the ideal timing for obtaining serum glucose level? |
|
| 176 |
11/08/2023 |
Recommended therapy for acute spinal cord infarction includes which of the following? |
|
| 177 |
10/08/2023 |
An 8-year-old girl presents to the clinic with frequent falls while running. She reports that her symptoms began 3 months ago when starting soccer practice and notes that, when trying to run, her legs would get stiff and feel funny. Sometimes, she would fall when this happened. On examination, when asked to run down the hall, she develops intorsion of the left foot and significant stiffening of the right leg. She is able to run backward well<br><br>What is the most appropriate therapy at this time? |
|
| 178 |
09/08/2023 |
A 40 year old male presents with slowly progressive leg weakness since a decade. He has findings of sensory motor neuropathy with pes cavus and areflexia. There is no history of diabetes or toxin exposure. There is history of similar illness in siblings and maternal uncles but not in maternal cousins. His mother has pes cavus. Nerve conduction study shows median nerve conduction to be 39ms. Abnormality in which gene is likely? |
|
| 179 |
08/08/2023 |
A 25 year old intern, working in the COVID ward complains of tightness around scalp without nausea or photophonophobia. It is especially prominent after covid duty, during which she wears a face shield and an N 95 mask. She denies prior migrainous headache<br><br>What is the diagnosis? |
|
| 180 |
07/08/2023 |
Parents noticed that their 9 month of infant does not respond to sounds. They brought him to a pediatrician, who noticed white forelock of hair on the infant. Baby had a broad nose, and beautiful blue eyes<br><br>What do you think went wrong during embryogenesis? |
|
| 181 |
06/08/2023 |
70 year old gentleman, presented with 2 month history of rapidly progressive cognitive decline, movement disorder- tremor, myoclonus, sleep disturbances- central sleep apnea, sleep parasomnias, periodic limb movements in sleep. He had severe shoulder pain, wasting and polyminimyoclonus. Skin changes like exfoliation present. He got seizures and status epilepticus<br><br>His MRI showed bilateral medial temporal hyperintense signal, and EEG showed bilateral temporal epileptiform discharges and slowing<br><br>Which antibody test will you send? |
|
| 182 |
05/08/2023 |
Which of the following surgical complications is more common with a posterior cervical surgical approach than with an anterior cervical surgical approach? |
|
| 183 |
04/08/2023 |
Which of the following causes of chorea is most commonly associated with seizures? |
|
| 184 |
03/08/2023 |
Which of these drugs does not cause a neuropathy mimicking CIDP? |
|
| 185 |
02/08/2023 |
In a patient with orgasmic headache, which of these statements is not true? |
|
| 186 |
01/08/2023 |
A 11 month old infant was not reciprocating to the sounds of his parents they showed his pediatrician, who ordered a BERA test which revealed severe sensorineural hearing loss. Child had normal developmental milestones for his age<br><br>MRI Brain was done which showed colpocephaly, partial agenesis of the corpus callosum, cerebellar dysplasia, arachnoid cysts, frontal subcortical heterotopia and frontal polymicrogyria<br><br>Which syndrome should you suspect in this child? |
|
| 187 |
31/07/2023 |
60 year old lady, diabetic had 2 strokes, there was progressive cognitive dysfunction after the stroke, however she would do all her activities of daily living independently. Her husband noticed that she is making mistakes while cooking at home. While making a sandwich she would bring chopped vegetables, cheese, bread correctly. But she would place two slices of bread, cut it, then put vegetables, and cut again. Her sequence of doing the task was incorrect. What is the most likely problem that she is suffering from? |
|
| 188 |
30/07/2023 |
A 21-year-old man presents with weakness and atrophy of the muscles of his right hand and forearm, which he first noticed at age 18 and has progressedvery gradually since then. He has no sensory symptoms and no symptoms inany other limb. Neurologic examination confirms the right forearm and intrinsic hand muscle weakness, sparing the brachioradialis, with no motor abnormality anywhere else in the body. Sensation and deep tendon reflexes are normal. Nerve conduction studies show normal sensory responses and moderate reduction of the right median and ulnar compound muscle action potential amplitudes with normal latencies. Needle EMG shows evidence of chronic denervation in the muscles that are clinically affected. A flexion cervical MRI is most likely to show which of the following abnormalities? |
|
| 189 |
29/07/2023 |
A neurology consult is requested for a 56-year-old man who is exhibiting abnormal jerking movements. Two weeks ago, while in the hospital for pneumonia, he went into sudden cardiorespiratory arrest. Resuscitation efforts in the hospital were successful after 7 minutes. He regained consciousness within 2 days of the arrest. On examination, he is ventilated through a tracheostomy and is not on any medications. He is able to open his eyes and raise both arms on command and show two fingers or a thumbs-up sign. He demonstrates uncontrollable jerking movements in his limbs and trunk whenever a movement is initiated. Basic metabolic panel and liver function are normal<br><br>Which of the following is the most likely diagnosis? |
|
| 190 |
28/07/2023 |
A 40 year old male presents with right grip weakness since 2 years. Examination reveals radial and ulnar weakness without sensory abnormalities. Nerve conduction studies show presence of motor conduction block with normal sensory responses. CSF and serum protein electrophoresis are normal. Which of these statements is true regarding the diagnosis of MMN (Multifocal motor neuropathy)? |
|
| 191 |
27/07/2023 |
In a patient with orgasmic headache, which of these statements is not true? |
|
| 192 |
26/07/2023 |
A 7-year-old boy presented with attention and behavioral difficulties. He was inattentive in school and needed to be reminded repeatedly. His mother said he daydreams most of the time. These symptoms were first noted approximately 9 months before presentation. Previously, he was normal in his preschool. His brother died at 1 year of age ?of an infection"<br><br>On examination, he had difficulty with comprehension, often asking for commands to be repeated, and abnormal expressive language. His neurologic examination revealed impaired tandem gait, brisk patellar reflexes, and extensor plantar responses<br><br>Brain MRI revealed T2 hyperintensities in the parietooccipital lobes bilaterally with an enhancing rim. |
|
| 193 |
25/07/2023 |
An 80 year old man, became irritable and confused on waking up. He was restless, collided with the door frame as he entered the room. He looked shabby, his spectacles were hanging, and he denied any problem. His neurological examination revealed sensory extinction and mild weakness on the left side. You test his reading ability and give him a newspaper. What is the most likely way in which he will read the paper? |
|
| 194 |
24/07/2023 |
A 54-year-old woman presents with an episode of transverse myelitis with severe quadriparesis that developed over 2 days. Spinal cord MRI demonstrates an extensive area of increased signal from T2 to T6, which enhances on postcontrast T1-weighted images. Brain MRI is normal. Which of the following laboratory results is most likely to be diagnostic in this patient? |
|
| 195 |
23/07/2023 |
A 44-year-old man develops a tremor after being fired from his job. The tremor started suddenly on the day he lost his job and worsens with stress<br><br>On examination, he has a coarse bilateral postural tremor that increases in amplitude upon weighting the limb, suppresses during contralateral ballistic movements, and entrains to a different examiner-given tapping frequency<br><br>What is the most important initial element in the management of this patient? |
|
| 196 |
22/07/2023 |
A 65 year old patient is newly diagnosed with Diabetes mellitus. His HbA1c is 12% and he is put on an intensive regimen to control sugars. After a month, he complains of severe neuropathic pain and postural hypotension. Nerve conduction study is normal. Which of these statements is true regarding his condition? |
|
| 197 |
21/07/2023 |
A 65 year old man presents with bouts of sharp stabbing pain around right eye and temple since several years. Attacks last for a minute, and recur 50 times a day. The pain causes redness and watering from the eye and a runny nose. Pain is triggered by washing the face and brushing the teeth. An MRI showed vascular loop in conflict with right trigeminal nerve<br><br>What is the likely diagnosis? |
|
| 198 |
20/07/2023 |
10 year old boy was referred by a pediatrician with a diagnosis of dystonic cerebral palsy<br><br>He was born of a non consanguineous marriage with normal developmental milestones, he had walking difficulty from 5 years of age. He had abnormal lower limb posturing, and neck posturing. On enquiry he said that his symptoms are worse in the evening ,as he is engaged in activities, improves markedly after sleep, on walking up in the morning<br><br>Examination revealed generalized dystonia, worse on walking. No KF ring<br><br>Which enzyme deficiency is not responsible for this disorder? |
|
| 199 |
19/07/2023 |
68 year old man has difficulty reading. He can write a sentence but cannot read his own words. On testing he has a right sided hemianopia. In addition to the occipital lobe which area is most likely affected? |
|
| 200 |
18/07/2023 |
A 33-year-old man sustained a severe spinal cord injury at the T10 level during a motor vehicle accident. During a prolonged rehabilitation with immobilization for healing of multiple fractures, he developed hip pain and decreased range of motion. Examination shows tender, warm nodular areas in the region around each hip. Plain films show calcifications within the soft tissues around his hip joints. Which of the following is a likely complication of his spinal cord injury represented by these findings? |
|
| 201 |
17/07/2023 |
A 77-year-old man without significant medical history presents for evaluation of falls and dysarthria. He started developing balance problems 1 to 2 years ago, which have been worsening significantly. He has fallen a number of times over the past year. His primary care physician evaluated him with a head CT that did not demonstrate any significant abnormalities. Over the past 3 months, he has developed slurring of his speech as well as difficulty swallowing. On examination, he demonstrates slowing of vertical saccades, decreased blink rate, square-wave jerks, Myerson sign, bilateral symmetric bradykinesia, increased neck tone, normal tone in the extremities, and slow gait with positive pull test<br><br>What is the most likely finding expected on MRI in this patient? |
|
| 202 |
16/07/2023 |
A 35 year old male presents with subacute progressive ataxia and numbness. Examination reveals sensory ataxia without motor weakness. Electrophysiological studies reveal normal sensory and motor conduction with absent SSEP. CSF shows elevated protein and lymphocytic pleocytosis with normal cytology. Serum protein electrophoresis is normal and PET scan has excluded a malignancy, but shows increased metabolic activity in the spinal roots. What is the diagnosis? |
|
| 203 |
15/07/2023 |
Which treatment has not been found to be effective for Cluster headache? |
|
| 204 |
14/07/2023 |
5 year old male child was diagnosed with intellectual disability, global developmental delay. He had dysmorphic features, arched eyebrows everted lower eyelids, widely spaced teeth and a flat nose. He had persistent fingertip pads. His MRI brain showed polymicrogyria. What is the most likely diagnosis? |
|
| 205 |
13/07/2023 |
Which of the following statements is not true regarding cerebellar cognitive syndrome? |
|
| 206 |
12/07/2023 |
Which of the following is most likely to be normal 3 months after trauma that resulted in complete loss of function of the left side of the spinal cord at the C6 level, but spared the right side of the spinal cord? |
|
| 207 |
11/07/2023 |
Which of the following features is more consistent with cortical, as opposed to subcortical, myoclonus? |
|
| 208 |
10/07/2023 |
Which of these neuropathies is not a nodopathy? |
|
| 209 |
09/07/2023 |
A 30 year old lady reports daily headache around left eye in afternoon since a month. Headache lasts for an hour and may sometimes recur in the night. There is redness and watering in the left eye during pain. She has nausea, photophobia and restlessness during the attack and it subsides abruptly. She had similar bout on right side at the same time two years ago which lasted a month, with milder left sided pain once a month. A trial of Indomethacin was unsuccessful<br><br>Which of these features reliably distinguish cluster from migraine? |
|
| 210 |
08/07/2023 |
38-years-old lady presented with insidious onset gradually progressive weakness in bilateral lower limbs since 10 years. She was a poor runner in school. She had wasting in intrinsic foot, hammer toes and pes cavus, which disappeared on standing. Neurological examination showed impaired joint position and vibration sense in both her feet till ankle. Similar foot deformities found in her 3 sisters and in her father. Nerve conduction study showed absent SNAPs and low amplitude CMAPs with conduction velocity 28 m/sec with uniform slowing. Which gene is most likely abnormal? |
|
| 211 |
07/07/2023 |
A 55 year old gentleman, bus driver by occupation, developed 3 year insidious onset progressive visuospatial difficulties, inattention, executive dysfunction, akinetic rigid syndrome, limb kinetic apraxia, dystonia of right upper limb<br><br>His extraocular movements were normal and there were mild memory deficits<br><br>His MRI brain showed left frontal-parieto-temporal atrophy<br><br>CSF A beta 42 levels were low and CSF tau was elevated<br><br>What is the diagnosis? |
|
| 212 |
06/07/2023 |
A 69-year-old man with myelopathy and pancytopenia is found to have copper deficiency. Of the following supplements on this patient?s medication list, which should he specifically be instructed to stop taking? |
|
| 213 |
05/07/2023 |
A 56-year-old man is evaluated for dyskinetic gait disorder. His gait is high-stepping, and he appears to strut on his toes, holding his elbows in a flexed position and his spine erect<br><br>Which of the following conditions is a likely cause of this gait disorder? |
|
| 214 |
04/07/2023 |
Which of these statements is true regarding POEMS (Polyneuropathy, organomegaly, endocrinopathy, Monoclonal plasma cell disorder and Skin changes) syndrome? |
|
| 215 |
03/07/2023 |
A 40 year old lady has chronic migraine with headache on most days of the month. She has been on Beta blocker, amitriptyline, topiramate and sodium valproate in various combination in the past without relief. She does not take triptan or NSAIDS as there is no relief. A CGRP monoclonal antibody has been started<br><br>Which statement is true regarding this treatment? |
|
| 216 |
02/07/2023 |
5 year old boy was posted for surgery of aganglionic megacolon. A neurology consult was asked for intellectual disability and history of seizures. Neurological examination showed exotropia. MRI brain showed corpus callosal agenesis. Which is the genetic defect suspected in this child? |
|
| 217 |
01/07/2023 |
A 55 year old lady, chartered accountant, presented with complaints of difficulty filing papers, making mistakes in taxation of clients, and mistakes in conducting regular company audits over the past 3 years. Her mistakes were increasing and she was given a memo in her job. She had insight about her problem and was frustrated. She had no difficulty navigating places, remembered names of people and could recollect recent events<br><br>Cognitive testing revealed severe executive dysfunction and mild memory impairment<br><br>MRI Brain was normal, FDG- PET scan showed severe hypometabolism on bilateral parietal lobes and left fronto-temporal lobe<br><br>What is the most likely diagnosis? |
|
| 218 |
30/06/2023 |
33-year-old woman with a history of uncontrolled HIV infection developed pain and weakness in both legs that progressed over severa months, and she has had urinary retention for the past week. Electrodiagnostic studies are consistent with lumbosacral polyradiculopathy. Lumbosacral MRI shows thickening and enhancement of the lumbosacral nerve roots at multiple levels. Lumbar puncture reveals neutrophilic pleocytosis. This syndrome is most likely due to infection by which of the following infectious agents? |
|
| 219 |
29/06/2023 |
A 35-year-old man presents for evaluation of head tremor. The tremor started 3 months ago and is associated with neck discomfort. He is not taking any medication and has no family history of a movement disorder. On examination, he has evidence of dystonic posturing of his neck with associated tremor, which worsens when his head is turned away from the direction of the dystonia<br><br>Which of the following treatments is most likely to be effective in this patient? |
|
| 220 |
28/06/2023 |
Which of these statements is true regarding treatment related fluctuations (TRF) in Guillain Barre syndrome? |
|
| 221 |
27/06/2023 |
A 50 year old lady has disabling migraine headaches every week. Initially her headaches would respond to paracetamol, but now she gets no relief despite taking two tablets. She had myocardial infarction one year ago and is on aspirin and statin. She is currently on Escitalopram 5 mg per day for anxiety. The prescribing doctor is contemplating triptan for acute treatment.<br><br>Which of these statements would be true regarding triptans for acute treatment? |
|
| 222 |
26/06/2023 |
Episodic ataxia type 2, Familial Hemiplegic migraine, Spinocerebellar ataxia type 6, epileptic encephalopathy, paroxysmal dystonia, autism spectrum disorder, learning disorders are associated with which of the following common genetic mutations? |
|
| 223 |
25/06/2023 |
Which of the following is not true regarding aducanumab? |
|
| 224 |
24/06/2023 |
Which of the following tests is most likely to be normal in a patient with cauda equina syndrome due to leptomeningeal spread of acute leukemia? |
|
| 225 |
23/06/2023 |
Which of the following nonpharmacologic approaches has been demonstrated to be beneficial for the management of tic disorders? |
|
| 226 |
22/06/2023 |
A 35 year old male presents with two weeks history of ascending weakness and areflexia. Which of these features will not be consistent with a diagnosis of Guillain barre syndrome? |
|
| 227 |
21/06/2023 |
Which of these statements is not true regarding premonitory symptoms of migraine? |
|
| 228 |
20/06/2023 |
60 year old male presented with gradually cerebellar ataxia. He developed tremors in both upper limbs,12-14Hz action + intention tremor, which disappeared at rest. He had recently developed short term memory loss and executive dysfunction. His MRI Brain showed bilateral MCP hyperintense signals. His grandson was diagnosed with autism and daughter had premature menopause. What will the patients genetic testing show? |
|
| 229 |
19/06/2023 |
A 35 years old male presented with acute meningitis syndrome. His CSF showed proteins 78 mg%, glucose 15 mg% and 350 cells with 90% neutrophils. His cultures did not grow any organism. He was treated with ceftriaxone and vancomycin in meningitic doses for 7 days. There were persistent symptoms even after 7 days. Repeat CSF at 7 days showed proteins 67 mg%, glucose 36 mg% and 170 cells with 85% neutrophils<br><br>What is the likely cause? |
|
| 230 |
18/06/2023 |
A middle aged lady developed fever, headache and drowsiness fr 2 days followed by weakness of all 4 limbs. Weakness was proximal as well as distal, with hyporeflexia and sensations were normal<br><br>CSF showed proteins 79 mg% with 22 cells. Nerve conduction study showed normal sensory conductions and reduced motor amplitudes<br><br>What is likely cause of it? |
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17/06/2023 |
Amongst the congenital CNS infections, all cause hearing loss except |
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16/06/2023 |
In case of congenital toxoplasmosis, the duration of treatment with sulfadiazine, pyrimethamine and leucovorin is
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