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Question
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Which of the following tumors is most commonly associated with opsoclonus-myoclonus?
Explanation
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Opsoclonus-myoclonus is a rare, disabling disorder in which a patient has rapid, involuntary, conjugate fast eye movements paired with diffuse myoclonus<br>This condition is most common in children, with about 50% paraneoplastic presentations related to neuroblastoma, and about 50% autoimmune (often parainfectious)<br>Opsoclonus-myoclonus may present in adults as well, either as autoimmune or as an anti-Ri (also known as anti-ANNA2)mediated paraneoplastic disorder related to small cell lung cancer, gynecological cancers, or breast cancers
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Reference
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Bradleys NiCP, 7th edn, Ch. 81
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Option 1
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Is Correct (Option 1):
Neuroblastoma
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Option 2
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Is Correct (Option 2):
Medulloblastoma
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Option 3
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Is Correct (Option 3):
Juvenile pilocytic astrocytoma
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Option 4
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Is Correct (Option 4):
Ependymoma
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