Quiz Form

Question Date: 04/11/2023

Question: Which of the following tumors is most commonly associated with opsoclonus-myoclonus?

Options:

Neuroblastoma
Medulloblastoma
Juvenile pilocytic astrocytoma
Ependymoma

Correct Answer: Neuroblastoma

Explaination: Opsoclonus-myoclonus is a rare, disabling disorder in which a patient has rapid, involuntary, conjugate fast eye movements paired with diffuse myoclonus<br>This condition is most common in children, with about 50% paraneoplastic presentations related to neuroblastoma, and about 50% autoimmune (often parainfectious)<br>Opsoclonus-myoclonus may present in adults as well, either as autoimmune or as an anti-Ri (also known as anti-ANNA2)mediated paraneoplastic disorder related to small cell lung cancer, gynecological cancers, or breast cancers