Quiz Form

Question Date: 17/01/2024

Question: Which of the following statement regarding "Treatment induced Neuropathy of Diabetes" is false?

Options:

Acute painful symptoms within 8 weeks of glycemic change
Risk and severity is proportional to rate of decrease in HbA1c and also the initial HbA1c level.
Reported in patients of type 2 diabetes on oral hypoglycemic agents
Symptoms are treatment responsive and anatomically restricted than the diabetic peripheral neuropathy

Correct Answer: Symptoms are treatment responsive and anatomically restricted than the diabetic peripheral neuropathy

Explaination: Treatment induced Neuropathy of Diabetes Initially described in patients with type1 Diabetes on Insulin(Insulin Neuritis term), it has been reported with type 2 diabetes as well as those on oral hypoglycemic agents. Drop in HbA1c of 2 % over 3 months confers higher risk Risk and severity increases with sudden rate of drop and initial HbA1c Acute Painful neuropathic and autonomic symptoms occur within 8 weeks of therapy Symptoms are more severe, treatment resistant and more anatomically extensive than diabetic radiculo-plexopathy and peripheral neuropathy Both neuropathic and autonomic symptoms improve over time.

Reference: Continuum : Neurology of Systemic Disease (June 2023, Volume 29,no 3) Neurological complications of Endocrine disorders. Page 897