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Question Date: 19/07/2023

Question: 68 year old man has difficulty reading. He can write a sentence but cannot read his own words. On testing he has a right sided hemianopia. In addition to the occipital lobe which area is most likely affected?

Options:

• Angular gyurs
• Anterior temporal lobe
• Cingulate gyurs
• Splenium of corpus callosum

Correct Answer: Splenium of corpus callosum

Explaination: Patient has alexia without agraphia, acquired inability to read but can write. Localization is left occipital cortex with extension to involve the splenium. Its is a disconnection syndrome, due to a disconnection between the intact right visual cortex & angular gyrus.

Reference: Barton, J. J. S. Higher Cortical Visual Deficits. CONTINUUM: Lifelong Learning in Neurology 20, 922 (2014).