Quiz Form
Quiz Form
Quiz Listing
Edit Question
1
2
3
Question Date
*
Please select a valid date.
Question
*
Which of these statements is true regarding MuSK myasthenia gravis?
Explanation
*
MuSK myasthenia comprises 50 % of generalized seronegative myasthenia gravis and shows a female predilection. Severe weakness and wasting of facial and bulbar muscles, including tongue may be seen. Patients with neck, shoulder and respiratory weakness may mimic a myopathy. Electrophysiology may show myopathic changes in weak muscles. Many patients do not respond to cholinesterase inhibitors, some worsen and show fasciculations. There are no thymic changes and thymectomy is not considered beneficial. MuSK antibody belongs to Ig G4 class and do not bind complement. Hence Eculizumab may not be useful.
Explanation Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
Reference
*
Rodolico C et al. MuSK-associated Myasthenia Gravis Clinical features and management. Front. Neurol. 2020
Reference Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
Question Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
Video Upload:
(MP4 / Upto 10 MB only)
Option 1
*
Is Correct (Option 1):
Musk myasthenia responds to cholinesterase inhibitors
Option 1 Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
Option 2
*
Is Correct (Option 2):
Wasting of tongue muscles may be seen
Option 2 Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
Option 3
*
Is Correct (Option 3):
Eculizumab is the most effective therapy for MuSK myasthenia
Option 3 Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
Option 4
*
Is Correct (Option 4):
It is more often associated with thymoma
Option 4 Image Upload:
(JPG / JPEG / PNG Upto 2 MB only)
