Quiz Form

Question Date: 21/02/2024

Question: Which of the following condition do not impair procedural memory?

Options:

• Parkinson's disease
• Huntington's disease
• Dementia with Lewy Bodies
• Olivopontocerebellar degeneration

Correct Answer: Dementia with Lewy Bodies

Explaination: Procedural memoryFunctional imaging has shown that brain regions involved in procedural memory, including the supplementary motor area, basal ganglia, and cerebellum, become active as a new task is being learnedLesions in the basal ganglia or cerebellum who show impairment in learning procedural skills.Disease process in early Alzheimers disease or dementia with lewy body affects cortical and limbic structures while sparing the basal ganglia and cerebellum, these patients show deficits in episodic memory but normal acquisition and maintenance of procedural skills. Parkinsons disease is the most common disorder affecting procedural memory. Other neurodegenerative diseases that disrupt procedural memory include Huntingtons disease and olivopontocerebellar degeneration. Patients in the early stages of these disorders perform nearly normally on episodic memory tests but show an impaired ability to learn skills.Tumors, strokes, hemorrhages and other causes of damage to the basal ganglia or cerebellum may also disrupt procedural memory.Patients with major depression have also been shown to have impairment in procedural memory, perhaps because depression may involve dysfunction of the basal ganglia

Reference: Andrew et al: Review article; Current concepts: Memory Dysfunction: N Engl J Med 2005;352:692-9