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Question
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Which of the following drugs are not recommended as neuropathic pain medication for chemotherapy induced peripheral neuropathy(CIPN)?
Explanation
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ASCO recommends use of Duloxetine in CIPN as best evidence drug<br>After that, TCAs,other SNRIs and gabapentinoids, mexiletine along with topical lidocaine gel can be used<br>Opiate pain medications work infrequently and worsens nausea, fatigue and constipation
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Reference
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Continuum : Peripheral nerve and motor neuron disorders (October 2023, Volume 29,no 5) Toxic neuropathies- Page 1457
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Option 1
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Is Correct (Option 1):
Mexiletine
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Option 2
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Is Correct (Option 2):
Lidocaine gel
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Option 3
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Is Correct (Option 3):
Tramadol
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Option 4
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Is Correct (Option 4):
Pregabalin
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