Quiz Form

Question Date: 26/09/2023

Question: Which of the following is false about imprinting?

Options:

• It is an epigenetic modification such as DNA or histone methylation
• It is a parent specific alteration which changes the DNA Sequence
• Loss of paternal patterning can lead to Angelman syndrome
• Loss of maternal patterning can lead to Prader-Willi syndrome

Correct Answer: It is a parent specific alteration which changes the DNA Sequence

Explaination: Imprinting is an epigenetic modification such as DNA or histone methylation which is parent specific and doesnt alter the DNA sequence.

Reference: Silveira-Moriyama, L. & Paciorkowski, A. R. Genetic Diagnostics for Neurologists CONTINUUM Lifelong Learning in Neurology 24, 1836 (2018).