Quiz Form

Question Date: 21/06/2023

Question: Which of these statements is not true regarding premonitory symptoms of migraine?

Options:

• Premonitory symptoms are not seen in migraine without aura
• Yawning and fatigue are common premonitory symptoms
• Hypothalamic activation is seen in the premonitory phase
• Drugs to abort an attack may be useful in the premonitory phase

Correct Answer: Premonitory symptoms are not seen in migraine without aura

Explaination: The premonitory phase of migraine consists of symptoms occurring hours to days before a migraine attack. These are common in all forms of migraine and in all ages. Common symptoms are yawning, concentration difficulty, fatigue, thirst, food craving, neck stiffness and photophobia. Studies have shown activation in the hypothalamus, brainstem and cortical areas such as the cingulate cortex in the premonitory phase. Domperidone and naratriptan have shown effect in aborting a migraine attack in the premonitory phase

Reference: Karsan N, Bose P. The Migraine Premonitory Phase. Continuum 2018;24(4): 996-1008.