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Question
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All of the below statements are true for Lennox-Gastaut Syndrome except..?
Explanation
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Myoclonic seizures: occur in 11-28% of patients and can lead to falls, but are associated with many generalized epilepsies and are therefore not regarded as a defining feature of LGS<br>Clinically characterized by multiple seizure types, Tonic seizures during sleep is the diagnostic feature<br>Abnormal EEG features of diagnostic significance include an interictal pattern of diffuse, slow spike-wave (SSW) complexes at <3Hz, occurring during wakefulness<br>Paroxysmal fast rhythms (10-20 Hz) during sleep, mainly during non-rapid eye movement sleep are the hallmark of tonic seizures
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Reference
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Blaise et al. Lennox-Gastaut Syndrome: A concensus approach to differential diagnosis. Epilepsia Oct 2014
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Option 1
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Is Correct (Option 1):
Diffuse, slow spike-wave (SSW) complexes at <3Hz, occur during wakefulness
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Option 2
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Is Correct (Option 2):
Myoclonic seizures associated with falls are diagnostic feature of LGS
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Option 3
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Is Correct (Option 3):
Paroxysmal fast rhythms (10-20 Hz) during sleep are hallmark of tonic seizures
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Option 4
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Is Correct (Option 4):
Non-convulsive status epilepticus is an important risk factor for cognitive impairment
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