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A 36yrs lady with refractory epilepsy, failed multiple ASMs, shows following imaging findings.What are the further treatment options?
Explanation
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Tuberous sclerosis:<br><br>Epilepsy occurs in 70% to 90% of patients, typically beginning in the first year of life<br>Refractory epilepsy is diagnosed in half of individuals with TSC and is predictive of development of intellectual disability<br>Introduction of an antiepileptic treatment during epileptogenesis and before the start of clinical seizures may prevent epilepsy onset and lead to a reduction in drug-resistant epilepsy<br>Everolimus proves as a add on treatment with response rate of 33% even at later age, without any age limit to individual benefit<br>Evaluation for epileptogenic tubers with FDG PET CT brain, if required SEEG for suspected lesions, followed by resectionThermoablation
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Option 1
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Is Correct (Option 1):
Valproate
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Option 2
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Is Correct (Option 2):
Everolimus
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Option 3
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Is Correct (Option 3):
Thermo-ablation
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Option 4
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Is Correct (Option 4):
All of the above
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