Question Date: 11/07/2023
Question: Which of the following features is more consistent with cortical, as opposed to subcortical, myoclonus?
Options:
Correct Answer: Provoked by tactile stimuli
Explaination: Symptomatic myoclonus is usually caused by cortical or subcortical lesions. Cortical myoclonus predominantly affects the face and hands, tends to be action induced, and is exacerbated or induced by tactile stimuli. Subcortical myoclonus tends to be more generalized or unilateral, is present both at rest and with action, and tends to be exacerbated or induced by auditory stimuli.
Reference: Espay AJ, Chen R. Myoclonus. Continuum (Minneap Minn). 2013 Oct;19(5 Movement Disorders):1264-86. doi: 10.1212/01.CON.0000436156.54532.1a. PMID: 24092290.