Quiz Form

Question Date: 15/01/2024

Question: Which of the following is true about acquired hepato-cerebral degeneration?

Options:

Reversible condition associated with altered level of consciousness
Ataxia plus and parkinsonian syndromes are most common presentations
Increased incidence found with increased duration and severity of liver disease
Higher cognitive functions with cortical dysfunction is predominant.

Correct Answer: Ataxia plus and parkinsonian syndromes are most common presentations

Explaination: Acquired hepato-cerebral degeneration irreversible neurologic condition seen in chronic liver disease It is uncommon, chronic progressive condition not associated with an altered level of consciousness. No relation found between incidence of the condition and nature, duration and severity of liver disease Movement disorders- Ataxia plus (Generalized ataxia with notable absence of nystagmus; plus- additional movement disorder or cerebellar findings) and Parkinsonian syndromes( Symmetric with prominent postural instability )are the most common presentations Most characteristic neuropsychiatric problems are psychomotor impairment, frontal lobe dysfunction and memory impairment Higher cognitive functions are less affected; cortical dysfunction is rare.

Reference: Continuum : Neurology of Systemic Disease (June 2023, Volume 29,no 3) Neurological manifestations of gastrointestinal and nutritional disorders; Page 724-725.