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Question
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Which of the following is true about acquired hepato-cerebral degeneration?
Explanation
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Acquired hepato-cerebral degeneration irreversible neurologic condition seen in chronic liver disease <br>It is uncommon, chronic progressive condition not associated with an altered level of consciousness.<br>No relation found between incidence of the condition and nature, duration and severity of liver disease<br>Movement disorders- Ataxia plus (Generalized ataxia with notable absence of nystagmus; plus- additional movement disorder or cerebellar findings) and Parkinsonian syndromes( Symmetric with prominent postural instability )are the most common presentations<br>Most characteristic neuropsychiatric problems are psychomotor impairment, frontal lobe dysfunction and memory impairment<br>Higher cognitive functions are less affected; cortical dysfunction is rare.
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Reference
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Continuum : Neurology of Systemic Disease (June 2023, Volume 29,no 3) Neurological manifestations of gastrointestinal and nutritional disorders; Page 724-725.
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Option 1
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Is Correct (Option 1):
Reversible condition associated with altered level of consciousness
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Option 2
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Is Correct (Option 2):
Ataxia plus and parkinsonian syndromes are most common presentations
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Option 3
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Is Correct (Option 3):
Increased incidence found with increased duration and severity of liver disease
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Option 4
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Is Correct (Option 4):
Higher cognitive functions with cortical dysfunction is predominant.
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