Question Date: 16/01/2024
Question: Which of the following neurologic syndrome does not show association with Rheumatoid Arthritis?
Options:
Correct Answer: CNS Demyelinating syndromes
Explaination: Rheumatoid arthritis<br><br>CNS manifestations<br>-Most common is cervical spinal stenosis due to synovitis and pannus formation at atlantoaxial, atlantooccipital joint<br>-Neck pain, C2 radiculopathy, myelopathy, respiratory involvement secondary to medullary compression<br>-Aseptic meningitis is rare but well described finding in long standing seropositive with absence of significant systemic disease activity.(Focal meningeal disease, pachy and leptomeningitis both can occur)<br>-Meningoencephalitis with headache seizures, focal deficits can occur<br>-Increased stroke risk due to accelerated atherosclerosis and cardiac involvement both can occur<br><br>PNS manifestations<br>-Axonal sensorimotor polyneuropathy, Entrapment neuropathies, Mononeuritis multiplex
Reference: Continuum : Neurology of Systemic Disease (June 2023, Volume 29,no 3) Neurological manifestations of gastrointestinal and nutritional disorders; Page 746-748, Table on Page 736-737.