Quiz Form

Question Date: 07/12/2023

Question: Which of the following medications slows the metabolism of dopamine in the central nervous system?

Options:

Rivastigmine
Trihexyphenidyl
Carbidopa
Entacapone

Correct Answer: Entacapone

Explaination: Entacapone is a catechol-O-methyl transferase inhibitor, which is one of the main enzymes responsible for the breakdown of dopamine in the central nervous system. The other main enzymes are monoamine oxidase B and dopamine beta hydroxylase (which converts dopamine to norepinephrine). Rivastigmine is an acetylcholinesterase inhibitor used in the treatment of Alzheimer disease and dementia with Parkinson disease. Trihexyphenidyl is an anticholinergic medication used in the treatment of dystonia. Carbidopa reduces the peripheral destruction of L-dopa (a precursor to dopamine), but does not affect central nervous system dopamine metabolism