Quiz Form

Question Date: 21/01/2024

Question: Which of the following is not a risk factor for development of post encephalitic epilepsy?

Options:

• Early anti seizure medication withdrawal
• Delayed initiation of immunotherapy
• History of status epilepticus
• High CSF protein level

Correct Answer: Early anti seizure medication withdrawal

Explaination: Risk factors for development of post encephalitic epilepsy include delayed initiation of immunotherapy, history of status epilepticus, interictal epileptiform discharges, high CSF protein level and antibody type.<br>Anti LGI1 and GABA-B antibodies have high propensity for seizure recurrence and epilepsy ; however anti NMDA has rare occurrence<br>Early or late withdrawal of antiseizure medication does not affect seizure outcome<br>Hence, antiseizure medication discontinuation does not influence the development of epilepsy.

Reference: Continuum : Epilepsy (April 2022, Volume 28,no 2) Autoimmune associated seizures; Page 378