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Question
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Which of the following myositis specific antibody does not have cancer association?
Explanation
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Cancer association is found in IIM in myositis specific antibodies such as TIF1 gamma, HMGCR,NXP2, SAE and rarely with anti SRP and anti MDA-5<br>Anti Mi-2 usually has good prognosis and does not show cancer association or risk of ILD
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Reference
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Continuum : Muscle and NM junction Disorders(December 2022, Volume 28,no 6)Inflammatory myopathies; Page no 1647
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Option 1
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Is Correct (Option 1):
TIF1 gamma
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Option 2
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Is Correct (Option 2):
Anti HMGCoA Reductase
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Option 3
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Is Correct (Option 3):
Anti Mi-2
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Option 4
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Is Correct (Option 4):
NXP-2
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