Quiz Form

Question Date: 08/10/2023

Question: Which of the following enzyme is responsible for clopidogrel resistance due to poor metabolism?

Options:

• CYP3A5
• CYP2C19
• CYP2C9
• CYP2C2

Correct Answer: CYP2C19

Explaination: Clopidogrel resistance occurs due to poor metabolizers of CYP2C19, especially alleles 2 and 3

Reference: Chan, A., Pirmohamed, M. & Comabella, M. Pharmacogenomics in neurology Current state and future steps. Annals of Neurology 70, 684697 (2011).