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A 56 Year old lady, developed subacute onset rapidly progressive gait ataxia, anterograde and retrograde amnesia, executive dysfunction, confabulation, apathy, as well as affective and social-cognitive impairments. Her oculomotor examination revealed ophthalmoparesis. She had multiple episodes of vomiting, anorexia prior to developing the neurological symptoms. MRI revealed bilateral Dorsomedial thalamic hyperintense signals. What is the most likely diagnosis?
Explanation
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Wernicke Korsakoff syndrome consists of rapidly progressive dementia, ataxia, ophthalmoplegia. Occurs due to thiamine deficiency.
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Reference
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Day, G. S. Rapidly Progressive Dementia. CONTINUUM Lifelong Learning in Neurology 28, 901 (2022).
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Option 1
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Is Correct (Option 1):
Korsakoff syndrome
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Option 2
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Is Correct (Option 2):
CJD
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Option 3
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Is Correct (Option 3):
Hashimoto encephalitis
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Option 4
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Is Correct (Option 4):
Coeliac disease
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